Clot Activator Blood Tubes: Fast Serum Preparation

Q1: What is the primary function of silica particles in clot activator tubes?

A: Silica particles activate the coagulation cascade through contact activation, shortening clotting time from 60+ minutes to 20-30 minutes. This reduces turnaround time for serum tests.

Q2: How does centrifugation impact clotted blood sample tube results?

A: Centrifugation at appropriate RCF (1300-2200g) separates serum effectively. Inadequate centrifugation may transfer cells or platelets, impacting chemistry results, while excessive force may cause hemolysis.

Q3: What distinguishes plain tube clot activator from serum separator tubes?

A: While both contain clot activators, serum separator tubes contain a gel barrier that moves during centrifugation to form a physical barrier between serum and clot, providing cleaner serum.

Q4: Are clot activator tubes suitable for coagulation studies?

A: No. Clot activator tubes interfere with coagulation tests. Sodium citrate tubes are recommended for coagulation panels to preserve coagulation factors.

Q5: What is the recommended storage protocol for clot activator blood collection tubes?

A: Store at room temperature (15-30°C), away from direct sunlight and extreme temperatures. Avoid freezing, which may compromise the activator coating integrity.

Q6: How soon after collection should gel tube with clot activator samples be centrifuged?

A: Ideal centrifugation should occur 30-60 minutes post-collection. Delays beyond 2 hours may cause cellular metabolites to diffuse into serum, affecting results.

Q7: Can clot activator tubes be used for blood bank collections?

A: For most blood bank testing, specifically tube typing, plain red-top tubes without additives are preferred to prevent interference with antigen-antibody reactions.